HSC-341 Science of Aging

Prerequisite: HSC-211
An in-depth analysis of aging, starting with changes occurring at the molecular and cellular level and analyzing their consequences at the organism level. The collective influence of these changes on organ function and their relationship to chronic diseases associated with aging, such as neurodegeneration, hypertension, atherosclerosis, diabetes, etc., will also be discussed. Primary topics will include: theories of aging; experimental models used to study aging and longevity; the impact of oxidative stress in cells and consequences on organ function; functional changes in the sensory organs, nervous system, cardiorespiratory system, endocrine system, immune system, musculoskeletal system; genetics of aging. 4 credits.